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Development of a particle swarm optimization-backpropagation artificial neural network model and effects of age and gender on pharmacokinetics study of omeprazole enteric-coated tablets in Chinese population

BACKGROUND: The effects of age and gender were explored on pharmacokinetics study of omeprazole enteric-coated tablets in Chinese population and a plasma concentration prediction model was developed. All the data (demographic characteristics and results of clinical laboratory tests) were collected f...

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Detalles Bibliográficos
Autores principales: Xu, Yichao, Chen, Jinliang, Yang, Dandan, Hu, Yin, Jiang, Bo, Ruan, Zourong, Lou, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295372/
https://www.ncbi.nlm.nih.gov/pubmed/35851436
http://dx.doi.org/10.1186/s40360-022-00594-2