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Functional Restoration of Exhausted CD8 T Cells in Chronic HIV-1 Infection by Targeting Mitochondrial Dysfunction

CD8 T cell exhaustion is a hallmark of HIV-1 infection, characterized by phenotypic and functional CD8 T cell abnormalities that persist despite years of effective antiretroviral treatment (ART). More recently, the importance of cellular metabolism in shaping T cell antiviral function has emerged as...

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Detalles Bibliográficos
Autores principales:	Alrubayyi, Aljawharah, Moreno-Cubero, Elia, Hameiri-Bowen, Dan, Matthews, Rebecca, Rowland-Jones, Sarah, Schurich, Anna, Peppa, Dimitra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295450/ https://www.ncbi.nlm.nih.gov/pubmed/35865519 http://dx.doi.org/10.3389/fimmu.2022.908697

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