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Multi-head attention-based U-Nets for predicting protein domain boundaries using 1D sequence features and 2D distance maps

The information about the domain architecture of proteins is useful for studying protein structure and function. However, accurate prediction of protein domain boundaries (i.e., sequence regions separating two domains) from sequence remains a significant challenge. In this work, we develop a deep le...

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Detalles Bibliográficos
Autores principales: Mahmud, Sajid, Guo, Zhiye, Quadir, Farhan, Liu, Jian, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295499/
https://www.ncbi.nlm.nih.gov/pubmed/35854211
http://dx.doi.org/10.1186/s12859-022-04829-1