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Integration of metabolites from meta-analysis with transcriptome reveals enhanced SPHK1 in PDAC with a background of pancreatitis

BACKGROUND: Pathophysiology of transformation of inflammatory lesions in chronic pancreatitis (CP) to pancreatic ductal adenocarcinoma (PDAC) is not clear. METHODS: We conducted a systematic review, meta-analysis of circulating metabolites, integrated this data with transcriptome analysis of human p...

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Detalles Bibliográficos
Autores principales: Ketavarapu, Vijayasarathy, Ravikanth, Vishnubhotla, Sasikala, Mitnala, Rao, G. V., Devi, Ch. Venkataramana, Sripadi, Prabhakar, Bethu, Murali Satyanarayana, Amanchy, Ramars, Murthy, H. V. V., Pandol, Stephen J., Reddy, D. Nageshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295503/
https://www.ncbi.nlm.nih.gov/pubmed/35854233
http://dx.doi.org/10.1186/s12885-022-09816-6