Cargando…

MBZM-N-IBT, a Novel Small Molecule, Restricts Chikungunya Virus Infection by Targeting nsP2 Protease Activity In Vitro, In Vivo, and Ex Vivo

The increase in disease incidences and persistent Chikungunya virus (CHIKV)-induced arthritis have been a huge burden on public health globally. In the absence of specific antivirals or vaccines, it is essential to continue efforts to develop effective anti-CHIKV strategies. Our previous study showi...

Descripción completa

Detalles Bibliográficos
Autores principales: De, Saikat, Ghosh, Soumyajit, Keshry, Supriya Suman, Mahish, Chandan, Mohapatra, Chinmayee, Guru, Ankeeta, Mamidi, Prabhudutta, Datey, Ankita, Pani, Sweta Smita, Vasudevan, Dileep, Beuria, Tushar Kant, Chattopadhyay, Subhasis, Subudhi, Bharat Bhusan, Chattopadhyay, Soma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295557/
https://www.ncbi.nlm.nih.gov/pubmed/35766508
http://dx.doi.org/10.1128/aac.00463-22