Cargando…
MBZM-N-IBT, a Novel Small Molecule, Restricts Chikungunya Virus Infection by Targeting nsP2 Protease Activity In Vitro, In Vivo, and Ex Vivo
The increase in disease incidences and persistent Chikungunya virus (CHIKV)-induced arthritis have been a huge burden on public health globally. In the absence of specific antivirals or vaccines, it is essential to continue efforts to develop effective anti-CHIKV strategies. Our previous study showi...
Autores principales: | De, Saikat, Ghosh, Soumyajit, Keshry, Supriya Suman, Mahish, Chandan, Mohapatra, Chinmayee, Guru, Ankeeta, Mamidi, Prabhudutta, Datey, Ankita, Pani, Sweta Smita, Vasudevan, Dileep, Beuria, Tushar Kant, Chattopadhyay, Subhasis, Subudhi, Bharat Bhusan, Chattopadhyay, Soma |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295557/ https://www.ncbi.nlm.nih.gov/pubmed/35766508 http://dx.doi.org/10.1128/aac.00463-22 |
Ejemplares similares
-
Inhibition of herpes simplex virus-1 infection by MBZM-N-IBT: in silico and in vitro studies
por: Kumar, Abhishek, et al.
Publicado: (2021) -
Inhibition of Chikungunya Virus Replication by 1-[(2-Methylbenzimidazol-1-yl) Methyl]-2-Oxo-Indolin-3-ylidene] Amino] Thiourea(MBZM-N-IBT)
por: Mishra, Priyadarsee, et al.
Publicado: (2016) -
DNA Damage Response Signaling Is Crucial for Effective Chikungunya Virus Replication
por: Chatterjee, Sanchari, et al.
Publicado: (2022) -
Protamine Sulfate Is a Potent Inhibitor of Human Papillomavirus Infection In Vitro and In Vivo
por: Young, Jesse M., et al.
Publicado: (2022) -
P38 and JNK Mitogen-Activated Protein Kinases Interact With Chikungunya Virus Non-structural Protein-2 and Regulate TNF Induction During Viral Infection in Macrophages
por: Nayak, Tapas Kumar, et al.
Publicado: (2019)