Mutation to ispA Produces Stable Small-Colony Variants of Pseudomonas aeruginosa That Have Enhanced Aminoglycoside Resistance

Pseudomonas aeruginosa is a major pathogen in burn wound infections. We present one of the first reports of small-colony variant (SCV) emergence of P. aeruginosa, taken from a patient under aminoglycosides for a persistent burn wound infection. We confirm the causative role of a single ispA mutation...

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Detalles Bibliográficos
Autores principales: Pitton, Melissa, Oberhaensli, Simone, Appiah, Fiona, Pagani, Jean-Luc, Fournier, Anne, Jakob, Stephan M., Que, Yok-Ai, Cameron, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295567/
https://www.ncbi.nlm.nih.gov/pubmed/35852364
http://dx.doi.org/10.1128/aac.00621-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295567/
https://www.ncbi.nlm.nih.gov/pubmed/35852364
http://dx.doi.org/10.1128/aac.00621-22

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