Characterizing SARS-CoV-2 Viral Clearance Kinetics to Improve the Design of Antiviral Pharmacometric Studies

A consensus methodology for the pharmacometric assessment of candidate SARS-CoV-2 antiviral drugs would be useful for comparing trial results and improving trial design. The time to viral clearance, assessed by serial qPCR of nasopharyngeal swab samples, has been the most widely reported measure of...

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Detalles Bibliográficos
Autores principales: Watson, James A., Kissler, Stephen M., Day, Nicholas P. J., Grad, Yonatan H., White, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295592/
https://www.ncbi.nlm.nih.gov/pubmed/35736134
http://dx.doi.org/10.1128/aac.00192-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295592/
https://www.ncbi.nlm.nih.gov/pubmed/35736134
http://dx.doi.org/10.1128/aac.00192-22

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