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A single local delivery of paclitaxel and nucleic acids via an immunoactive polymer eliminates tumors and induces antitumor immunity

Despite recent advances in cancer therapy, hard-to-reach, unidentified tumors remain a significant clinical challenge. A promising approach is to treat locatable and accessible tumors locally and stimulate antitumor immunity in situ to exert systemic effects against distant tumors. We hypothesize th...

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Detalles Bibliográficos
Autores principales: Meng, Fanfei, Wang, Jianping, He, Yanying, Cresswell, Gregory M., Lanman, Nadia A., Lyle, L. Tiffany, Ratliff, Timothy L., Yeo, Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295735/
https://www.ncbi.nlm.nih.gov/pubmed/35609195
http://dx.doi.org/10.1073/pnas.2122595119