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A brain-enriched lncRNA shields cancer cells from immune-mediated killing for metastatic colonization in the brain

Brain metastases, including prevalent breast-to-brain metastasis (B2BM), represent an urgent unmet medical need in the care of cancer due to a lack of effective therapies. Immune evasion is essential for cancer cells to metastasize to the brain tissue for brain metastasis. However, the intrinsic gen...

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Detalles Bibliográficos
Autores principales: Liu, Weiguang, Sun, Peng, Xia, Lingling, He, Xilin, Xia, Zhengmiao, Huang, Yehong, Liu, Wenzhuo, Li, Lulu, Chen, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295751/
https://www.ncbi.nlm.nih.gov/pubmed/35617432
http://dx.doi.org/10.1073/pnas.2200230119