The HDAC inhibitor CI-994 acts as a molecular memory aid by facilitating synaptic and intracellular communication after learning

Long-term memory formation relies on synaptic plasticity, neuronal activity-dependent gene transcription, and epigenetic modifications. Multiple studies have shown that HDAC inhibitor (HDACi) treatments can enhance individual aspects of these processes and thereby act as putative cognitive enhancers...

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Detalles Bibliográficos
Autores principales: Burns, Allison M., Farinelli-Scharly, Mélissa, Hugues-Ascery, Sandrine, Sanchez-Mut, Jose Vicente, Santoni, Giulia, Gräff, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295763/
https://www.ncbi.nlm.nih.gov/pubmed/35613054
http://dx.doi.org/10.1073/pnas.2116797119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295763/
https://www.ncbi.nlm.nih.gov/pubmed/35613054
http://dx.doi.org/10.1073/pnas.2116797119

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