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Generation of dynamic three-dimensional genome structure through phase separation of chromatin

Three-dimensional genome structure and dynamics play critical roles in regulating DNA functions. Flexible chromatin structure and movements suggested that the genome is dynamically phase separated to form A (active) and B (inactive) compartments in interphase nuclei. Here, we examine this hypothesis...

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Detalles Bibliográficos
Autores principales: Fujishiro, Shin, Sasai, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295772/
https://www.ncbi.nlm.nih.gov/pubmed/35617433
http://dx.doi.org/10.1073/pnas.2109838119