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Generation of dynamic three-dimensional genome structure through phase separation of chromatin
Three-dimensional genome structure and dynamics play critical roles in regulating DNA functions. Flexible chromatin structure and movements suggested that the genome is dynamically phase separated to form A (active) and B (inactive) compartments in interphase nuclei. Here, we examine this hypothesis...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295772/ https://www.ncbi.nlm.nih.gov/pubmed/35617433 http://dx.doi.org/10.1073/pnas.2109838119 |