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Structure of Arp2/3 complex at a branched actin filament junction resolved by single-particle cryo-electron microscopy

Arp2/3 complex nucleates branched actin filaments that provide pushing forces to drive cellular processes such as lamellipodial protrusion and endocytosis. Arp2/3 complex is intrinsically inactive, and multiple classes of nucleation promoting factors (NPFs) stimulate its nucleation activity. When ac...

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Detalles Bibliográficos
Autores principales: Ding, Bojian, Narvaez-Ortiz, Heidy Y., Singh, Yuvraj, Hocky, Glen M., Chowdhury, Saikat, Nolen, Brad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295785/
https://www.ncbi.nlm.nih.gov/pubmed/35622886
http://dx.doi.org/10.1073/pnas.2202723119