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Translation initiation site of mRNA is selected through dynamic interaction with the ribosome
Initiation of protein synthesis from the correct start codon of messenger RNA (mRNA) is crucial to translation fidelity. In bacteria, the start codon is usually preceded by a 4- to 6-mer adenosine/guanosine-rich Shine–Dalgarno (SD) sequence. Both the SD sequence and the start codon comprise the core...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295790/ https://www.ncbi.nlm.nih.gov/pubmed/35605125 http://dx.doi.org/10.1073/pnas.2118099119 |