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Double stranded DNA breaks and genome editing trigger loss of ribosomal protein RPS27A

DNA damage activates a robust transcriptional stress response, but much less is known about how DNA damage impacts translation. The advent of genome editing with Cas9 has intensified interest in understanding cellular responses to DNA damage. Here, we find that DNA double‐strand breaks (DSBs), inclu...

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Detalles Bibliográficos
Autores principales: Riepe, Celeste, Zelin, Elena, Frankino, Phillip A., Meacham, Zuriah A., Fernandez, Samantha G., Ingolia, Nicholas T., Corn, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295824/
https://www.ncbi.nlm.nih.gov/pubmed/34914197
http://dx.doi.org/10.1111/febs.16321