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Antibody-Targeted TNFRSF Activation for Cancer Immunotherapy: The Role of FcγRIIB Cross-Linking

Co-stimulation signaling in various types of immune cells modulates immune responses in physiology and disease. Tumor necrosis factor receptor superfamily (TNFRSF) members such as CD40, OX40 and CD137/4-1BB are expressed on myeloid cells and/or lymphocytes, and they regulate antigen presentation and...

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Detalles Bibliográficos
Autores principales: Liu, Luyan, Wu, Yi, Ye, Kaiyan, Cai, Meichun, Zhuang, Guanglei, Wang, Jieyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295861/
https://www.ncbi.nlm.nih.gov/pubmed/35865955
http://dx.doi.org/10.3389/fphar.2022.924197