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Investigation of Functional Synergism of CENPF and FOXM1 Identifies POLD1 as Downstream Target in Hepatocellular Carcinoma

BACKGROUND: Lines of evidence implicate CENPF and FOXM1 may have novel co-operative roles in driving hepatocellular carcinoma (HCC). OBJECTIVE: We investigated the clinicopathological correlation, functional characterization, molecular mechanism and translational significance of CENPF and FOXM1. MET...

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Detalles Bibliográficos
Autores principales: Ho, Daniel Wai-Hung, Lam, Wai-Ling Macrina, Chan, Lo-Kong, Ng, Irene Oi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295863/
https://www.ncbi.nlm.nih.gov/pubmed/35865168
http://dx.doi.org/10.3389/fmed.2022.860395