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Alternative splicing of METTL3 explains apparently METTL3-independent m(6)A modifications in mRNA
N(6)-methyladenosine (m(6)A) is a highly prevalent mRNA modification that promotes degradation of transcripts encoding proteins that have roles in cell development, differentiation, and other pathways. METTL3 is the major methyltransferase that catalyzes the formation of m(6)A in mRNA. As 30% to 80%...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295969/ https://www.ncbi.nlm.nih.gov/pubmed/35853000 http://dx.doi.org/10.1371/journal.pbio.3001683 |