Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells

Human immune deficiency virus (HIV) infection in the brain leads to chronic neuroinflammation due to the production of pro-inflammatory cytokines, which in turn promotes HIV transcription in infected microglial cells. However, powerful counteracting silencing mechanisms in microglial cells result in...

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Detalles Bibliográficos
Autores principales: Ye, Fengchun, Alvarez-Carbonell, David, Nguyen, Kien, Leskov, Konstantin, Garcia-Mesa, Yoelvis, Sreeram, Sheetal, Valadkhan, Saba, Karn, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295971/
https://www.ncbi.nlm.nih.gov/pubmed/35797416
http://dx.doi.org/10.1371/journal.ppat.1010110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295971/
https://www.ncbi.nlm.nih.gov/pubmed/35797416
http://dx.doi.org/10.1371/journal.ppat.1010110

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