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Modeling congenital heart disease: lessons from mice, hPSC-based models, and organoids

Congenital heart defects (CHDs) are among the most common birth defects, but their etiology has long been mysterious. In recent decades, the development of a variety of experimental models has led to a greater understanding of the molecular basis of CHDs. In this review, we contrast mouse models of...

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Detalles Bibliográficos
Autores principales: Rao, Kavitha S., Kameswaran, Vasumathi, Bruneau, Benoit G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296004/
https://www.ncbi.nlm.nih.gov/pubmed/35835508
http://dx.doi.org/10.1101/gad.349678.122