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Upstream open reading frames control PLK4 translation and centriole duplication in primordial germ cells

Centrosomes are microtubule-organizing centers comprised of a pair of centrioles and the surrounding pericentriolar material. Abnormalities in centriole number are associated with cell division errors and can contribute to diseases such as cancer. Centriole duplication is limited to once per cell cy...

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Detalles Bibliográficos
Autores principales: Phan, Thao P., Boatwright, Christina A., Drown, Chelsea G., Skinner, Marnie W., Strong, Margaret A., Jordan, Philip W., Holland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296005/
https://www.ncbi.nlm.nih.gov/pubmed/35772791
http://dx.doi.org/10.1101/gad.349604.122