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Balancing the scales: fine-tuning Polo-like kinase 4 to ensure proper centriole duplication
Polo-like kinase 4 (Plk4) is the master regulator of centriole assembly. Several evolutionarily conserved mechanisms strictly regulate Plk4 abundance and activity to ensure cells maintain a proper number of centrioles. In this issue of Genes & Development, Phan et al. (pp. 718–736) add to this g...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296006/ https://www.ncbi.nlm.nih.gov/pubmed/35835509 http://dx.doi.org/10.1101/gad.349815.122 |