A peptide interfering with the dimerization of oncogenic KITENIN protein and its stability suppresses colorectal tumour progression

The stability of a protein, as well as its function and versatility, can be enhanced through oligomerization. KITENIN (KAI1 C‐terminal interacting tetraspanin) is known to promote the malignant progression of colorectal cancer (CRC). How KITENIN maintains its structural integrity and stability are l...

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Detalles Bibliográficos
Autores principales: Kim, Sung Jin, Sun, Eun Gene, Bae, Jeong A, Park, Sehoon, Hong, Chang‐Soo, Park, Zee‐Yong, Kim, Hangun, Kim, Kyung Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296036/
https://www.ncbi.nlm.nih.gov/pubmed/35853101
http://dx.doi.org/10.1002/ctm2.871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296036/
https://www.ncbi.nlm.nih.gov/pubmed/35853101
http://dx.doi.org/10.1002/ctm2.871

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