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Characterization of the Genomic and Immunologic Diversity of Malignant Brain Tumors through Multisector Analysis

Despite some success in secondary brain metastases, targeted or immune-based therapies have shown limited efficacy against primary brain malignancies such as glioblastoma (GBM). Although the intratumoral heterogeneity of GBM is implicated in treatment resistance, it remains unclear whether this dive...

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Detalles Bibliográficos
Autores principales: Schaettler, Maximilian O., Richters, Megan M., Wang, Anthony Z., Skidmore, Zachary L., Fisk, Bryan, Miller, Katherine E., Vickery, Tammi L., Kim, Albert H., Chicoine, Michael R., Osbun, Joshua W., Leuthardt, Eric C., Dowling, Joshua L., Zipfel, Gregory J., Dacey, Ralph G., Lu, Hsiang-Chih, Johanns, Tanner M., Griffith, Obi L., Mardis, Elaine R., Griffith, Malachi, Dunn, Gavin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296070/
https://www.ncbi.nlm.nih.gov/pubmed/34610950
http://dx.doi.org/10.1158/2159-8290.CD-21-0291