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Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth

The nuclear envelope (NE) assembles and grows from bilayer lipids produced at the endoplasmic reticulum (ER). How ER membrane incorporation coordinates with assembly of nuclear pore complexes (NPCs) to generate a functional NE is not well understood. Here, we use the stereotypical first division of...

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Detalles Bibliográficos
Autores principales: Mauro, Michael Sean, Celma, Gunta, Zimyanin, Vitaly, Magaj, Magdalena M, Gibson, Kimberley H, Redemann, Stefanie, Bahmanyar, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296133/
https://www.ncbi.nlm.nih.gov/pubmed/35852146
http://dx.doi.org/10.7554/eLife.75513