Design of a specific peptide against phenolic glycolipid-1 from Mycobacterium leprae and its implications in leprosy bacilli entry

BACKGROUND: Mycobacterium leprae, the causative agent of Hansen’s disease, causes neural damage through the specific interaction between the external phenolic glycolipid-1 (PGL-1) and laminin subunit alpha-2 (LAMA2) from Schwann cells. OBJECTIVE: To design a LAMA2-based peptide that targets PGL-1 fr...

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Detalles Bibliográficos
Autores principales: Arenas, Nelson Enrique, Pieffet, Gilles, Rocha-Roa, Cristian, Guerrero, Martha Inírida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296141/
https://www.ncbi.nlm.nih.gov/pubmed/35857971
http://dx.doi.org/10.1590/0074-02760220025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296141/
https://www.ncbi.nlm.nih.gov/pubmed/35857971
http://dx.doi.org/10.1590/0074-02760220025

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