Whole-body metabolic modelling predicts isoleucine dependency of SARS-CoV-2 replication

We aimed at investigating host-virus co-metabolism during SARS-CoV-2 infection. Therefore, we extended comprehensive sex-specific, whole-body organ resolved models of human metabolism with the necessary reactions to replicate SARS-CoV-2 in the lung as well as selected peripheral organs. Using this c...

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Detalles Bibliográficos
Autores principales: Thiele, Ines, Fleming, Ronan M.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296228/
https://www.ncbi.nlm.nih.gov/pubmed/35874091
http://dx.doi.org/10.1016/j.csbj.2022.07.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296228/
https://www.ncbi.nlm.nih.gov/pubmed/35874091
http://dx.doi.org/10.1016/j.csbj.2022.07.019

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