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TGF-β1 Induces Interlukin-11 Expression and Pro-Fibrotic Effect by DNA Demethylation in Subconjunctival Fibroblasts

OBJECTIVE: To assess Interlukin-11 (IL11) expression in the tears of patients after filtration surgery and to find out its pro-transdifferentiational and pro-fibrotic functions and mechanisms on subconjunctival human Tenon's capsule fibroblasts (HTFs) induced by transforming growth factor beta1...

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Detalles Bibliográficos
Autores principales: Fu, Shuhao, Lu, Zhaozeng, Ye, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296281/
https://www.ncbi.nlm.nih.gov/pubmed/35865343
http://dx.doi.org/10.1155/2022/7729827