SLC6A14 Depletion Contributes to Amino Acid Starvation to Suppress EMT-Induced Metastasis in Gastric Cancer by Perturbing the PI3K/AKT/mTORC1 Pathway

Metastasis is the main obstacle for the treatment of gastric cancer (GC), leading to low survival rate and adverse outcomes in CG patients. SLC6A14, a general amino acid transporter, can import all the essential amino acids in a manner dependent on the NaCl-generated osmotic gradients. Herein, we co...

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Detalles Bibliográficos
Autores principales: Guo, Qie, Xu, Wen, Li, Xiao, Sun, Jia-Lin, Gu, Xiao-Ce, Jing, Fan-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296317/
https://www.ncbi.nlm.nih.gov/pubmed/35865664
http://dx.doi.org/10.1155/2022/7850658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296317/
https://www.ncbi.nlm.nih.gov/pubmed/35865664
http://dx.doi.org/10.1155/2022/7850658

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