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SLC6A14 Depletion Contributes to Amino Acid Starvation to Suppress EMT-Induced Metastasis in Gastric Cancer by Perturbing the PI3K/AKT/mTORC1 Pathway
Metastasis is the main obstacle for the treatment of gastric cancer (GC), leading to low survival rate and adverse outcomes in CG patients. SLC6A14, a general amino acid transporter, can import all the essential amino acids in a manner dependent on the NaCl-generated osmotic gradients. Herein, we co...
Autores principales: | Guo, Qie, Xu, Wen, Li, Xiao, Sun, Jia-Lin, Gu, Xiao-Ce, Jing, Fan-Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296317/ https://www.ncbi.nlm.nih.gov/pubmed/35865664 http://dx.doi.org/10.1155/2022/7850658 |
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