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Activation of the hypoxia response protects mice from amyloid-β accumulation

Alzheimer’s disease (AD) is the most common cause of dementia with limited treatment options affecting millions of people and the prevalence increasing with the aging population. The current knowledge on the role of the hypoxia/hypoxia-inducible factor (HIF) in the AD pathology is restricted and con...

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Detalles Bibliográficos
Autores principales: Ollonen, Teemu, Kurkela, Margareta, Laitakari, Anna, Sakko, Samuli, Koivisto, Henna, Myllyharju, Johanna, Tanila, Heikki, Serpi, Raisa, Koivunen, Peppi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296391/
https://www.ncbi.nlm.nih.gov/pubmed/35852609
http://dx.doi.org/10.1007/s00018-022-04460-6