Cargando…
Reactivity-dependent profiling of RNA 5-methylcytidine dioxygenases
Epitranscriptomic RNA modifications can regulate fundamental biological processes, but we lack approaches to map modification sites and probe writer enzymes. Here we present a chemoproteomic strategy to characterize RNA 5-methylcytidine (m(5)C) dioxygenase enzymes in their native context based upon...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296451/ https://www.ncbi.nlm.nih.gov/pubmed/35853884 http://dx.doi.org/10.1038/s41467-022-31876-2 |