Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A)

N-Glycosylation is a common post-translational modification, and the number of GlcNAc branches in N-glycans impacts glycoprotein functions. N-Acetylglucosaminyltransferase-IVa (GnT-IVa, also designated as MGAT4A) forms a β1-4 GlcNAc branch on the α1-3 mannose arm in N-glycans. Downregulation or loss...

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Detalles Bibliográficos
Autores principales: Nagae, Masamichi, Hirata, Tetsuya, Tateno, Hiroaki, Mishra, Sushil K., Manabe, Noriyoshi, Osada, Naoko, Tokoro, Yuko, Yamaguchi, Yoshiki, Doerksen, Robert J., Shimizu, Toshiyuki, Kizuka, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296478/
https://www.ncbi.nlm.nih.gov/pubmed/35854001
http://dx.doi.org/10.1038/s42003-022-03661-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296478/
https://www.ncbi.nlm.nih.gov/pubmed/35854001
http://dx.doi.org/10.1038/s42003-022-03661-w

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