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PTHrP promotes subchondral bone formation in TMJ-OA

PTH-related peptide (PTHrP) improves the bone marrow micro-environment to activate the bone-remodelling, but the coordinated regulation of PTHrP and transforming growth factor-β (TGFβ) signalling in TMJ-OA remains incompletely understood. We used disordered occlusion to establish model animals that...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Pi, Caixia, Cui, Chen, Zhou, Yang, Liu, Bo, Liu, Juan, Xu, Xin, Zhou, Xuedong, Zheng, Liwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296483/
https://www.ncbi.nlm.nih.gov/pubmed/35853862
http://dx.doi.org/10.1038/s41368-022-00189-x