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Predicting mortality among ischemic stroke patients using pathways-derived polygenic risk scores

We aim to determine whether ischemic stroke(IS)-related PRSs are also associated with and further predict 3-year all-cause mortality. 1756 IS patients with European ancestry were randomly split into training (n = 1226) and testing (n = 530) groups with 3-year post-event observations. Univariate Cox...

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Detalles Bibliográficos
Autores principales: Li, Jiang, Chaudhary, Durgesh, Griessenauer, Christoph J., Carey, David J., Zand, Ramin, Abedi, Vida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296485/
https://www.ncbi.nlm.nih.gov/pubmed/35853973
http://dx.doi.org/10.1038/s41598-022-16510-x