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SIRT1 upregulation promotes epithelial-mesenchymal transition by inducing senescence escape in endometriosis
Endometrial epithelial cells carry distinct cancer-associated alterations that may be more susceptible to endometriosis. Mouse models have shown that overexpression of SIRT1 associated with oncogene activation contributes to the pathogenesis of endometriosis, but the underlying reason remains elusiv...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296487/ https://www.ncbi.nlm.nih.gov/pubmed/35853978 http://dx.doi.org/10.1038/s41598-022-16629-x |