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SIRT1 upregulation promotes epithelial-mesenchymal transition by inducing senescence escape in endometriosis

Endometrial epithelial cells carry distinct cancer-associated alterations that may be more susceptible to endometriosis. Mouse models have shown that overexpression of SIRT1 associated with oncogene activation contributes to the pathogenesis of endometriosis, but the underlying reason remains elusiv...

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Detalles Bibliográficos
Autores principales: Wang, Minghua, Wu, Yongqi, He, Yunbiao, Liu, Jing, Chen, Yingxing, Huang, Jieqiong, Qi, Guolong, Li, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296487/
https://www.ncbi.nlm.nih.gov/pubmed/35853978
http://dx.doi.org/10.1038/s41598-022-16629-x