Interplay of Nrf2 and BACH1 in inducing ferroportin expression and enhancing resistance of human macrophages towards ferroptosis

Compared to cancer cells, macrophages are inert to lipid peroxidation-triggered, iron-dependent cell death known as ferroptosis. Mechanisms underlying macrophage resistance towards ferroptosis are largely obscure. Here, we show that human primary macrophages respond to RSL3, a ferroptosis-inducing i...

Descripción completa

Detalles Bibliográficos
Autores principales: Namgaladze, Dmitry, Fuhrmann, Dominik C., Brüne, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296510/
https://www.ncbi.nlm.nih.gov/pubmed/35853860
http://dx.doi.org/10.1038/s41420-022-01117-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296510/
https://www.ncbi.nlm.nih.gov/pubmed/35853860
http://dx.doi.org/10.1038/s41420-022-01117-y

Ejemplares similares