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Inhibition of TWEAK/Tnfrsf12a axis protects against acute liver failure by suppressing RIPK1-dependent apoptosis

Acute liver failure (ALF) is a severe clinical syndrome characterized by massive death of hepatocytes in a short time, resulting in coagulopathy and hepatic encephalopathy, with a high mortality in patients without pre-existing liver disease. Effective treatment of ALF is currently limited to liver...

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Detalles Bibliográficos
Autores principales: Li, Zhijie, Wang, Heming, Zhu, Junjin, Nan, Ning, Lin, Yi, Zhuang, Xuran, Li, Ling, Zhang, Yamin, Huang, Pengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296540/
https://www.ncbi.nlm.nih.gov/pubmed/35853848
http://dx.doi.org/10.1038/s41420-022-01123-0