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Bedaquiline exposure in pregnancy and breastfeeding in women with rifampicin‐resistant tuberculosis

AIMS: We aimed to explore the effect of pregnancy on bedaquiline pharmacokinetics (PK) and describe bedaquiline exposure in the breast milk of mothers treated for rifampicin‐resistant tuberculosis (TB), where there are no human data available. METHODS: We performed a longitudinal PK study in pregnan...

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Detalles Bibliográficos
Autores principales: Court, Richard, Gausi, Kamunkhwala, Mkhize, Buyisile, Wiesner, Lubbe, Waitt, Catriona, McIlleron, Helen, Maartens, Gary, Denti, Paolo, Loveday, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296589/
https://www.ncbi.nlm.nih.gov/pubmed/35526837
http://dx.doi.org/10.1111/bcp.15380