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Population pharmacokinetics of tenofovir, emtricitabine and intracellular metabolites in transgender women

AIMS: Transgender women (TGW) have been underrepresented in trials and use gender‐affirming hormonal therapies (GAHT) that may alter renal function by significantly increasing creatinine clearance. Population pharmacokinetic (popPK) models and simulations would aid in understanding potential differe...

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Detalles Bibliográficos
Autores principales: Tanaudommongkon, Asama, Chaturvedula, Ayyappa, Hendrix, Craig W., Fuchs, Edward J., Shieh, Eugenie, Bakshi, Rahul P., Marzinke, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296590/
https://www.ncbi.nlm.nih.gov/pubmed/35285974
http://dx.doi.org/10.1111/bcp.15310