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Activation function 1 of progesterone receptor is required for mammary development and regulation of RANKL during pregnancy
Progesterone receptor (PGR) is a member of the nuclear receptor superfamily of transcription factors. It is critical for mammary stem cells expansion, mammary ductal branching and alveologenesis. The transcriptional activity of PGR is mainly mediated by activation functions AF1 and AF2. Although the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296660/ https://www.ncbi.nlm.nih.gov/pubmed/35854046 http://dx.doi.org/10.1038/s41598-022-16289-x |