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A prognostic hypoxia gene signature with low heterogeneity within the dominant tumour lesion in prostate cancer patients

BACKGROUND: Gene signatures measured in a biopsy have been proposed as hypoxia biomarkers in prostate cancer. We assessed a previously developed signature, and aimed to determine its relationship to hypoxia and its heterogeneity within the dominant (index) lesion of prostate cancer. METHODS: The 32-...

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Detalles Bibliográficos
Autores principales: Salberg, Unn Beate, Skingen, Vilde Eide, Fjeldbo, Christina Sæten, Hompland, Tord, Ragnum, Harald Bull, Vlatkovic, Ljiljana, Hole, Knut Håkon, Seierstad, Therese, Lyng, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296675/
https://www.ncbi.nlm.nih.gov/pubmed/35332267
http://dx.doi.org/10.1038/s41416-022-01782-x