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Small-scale dosimetry for alpha particle (241)Am source cell irradiation and estimation of γ-H2AX foci distribution in prostate cancer cell line PC3

BACKGROUND: The development of new targeted alpha therapies motivates improving alpha particle dosimetry. For alpha particles, microscopic targets must be considered to estimate dosimetric quantities that can predict the biological response. As double-strand breaks (DSB) on DNA are the main cause of...

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Detalles Bibliográficos
Autores principales: Mellhammar, Emma, Dahlbom, Magnus, Vilhelmsson-Timmermand, Oskar, Strand, Sven-Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296737/
https://www.ncbi.nlm.nih.gov/pubmed/35852717
http://dx.doi.org/10.1186/s40658-022-00475-x