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The Roles of ATP13A2 Gene Mutations Leading to Abnormal Aggregation of α-Synuclein in Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease. PARK9 (also known as ATP13A2) is recognized as one of the key genes that cause PD, and a mutation in this gene was first discovered in a rare case of PD in an adolescent. Lewy bodies (LBs) formed by abnormal aggregation of...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Wu, Zhiwei, Long, Fei, Tan, Jieqiong, Gong, Ni, Li, Xiaorong, Lin, Changwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296842/
https://www.ncbi.nlm.nih.gov/pubmed/35875356
http://dx.doi.org/10.3389/fncel.2022.927682