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Role of ERK signaling in bladder urothelium in response to cyclophosphamide injury

Mice with inducible urothelial deletion of fibroblast growth factor receptor 2 (ShhCreERT2;Fgfr2 ( Fl/Fl )) injured with cyclophosphamide had aberrant basal cell endoreplication and poor regeneration. The endoreplication correlated with an absence of phosphorylated (activated) ERK expression in urot...

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Detalles Bibliográficos
Autores principales: Narla, Sridhar Tatarao, Duara, Joanne Lindsey, Bushnell, Daniel Scott, Nouraie, Mehdi, Holden, Jacqueline, Pfister, Katherine, Lucas, Peter C., Sims‐Lucas, Sunder, Bates, Carlton Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296905/
https://www.ncbi.nlm.nih.gov/pubmed/35854647
http://dx.doi.org/10.14814/phy2.15378