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Integrin αvβ3 Induces HSP90 Inhibitor Resistance via FAK Activation in KRAS-Mutant Non–Small Cell Lung Cancer
PURPOSE: Heat shock protein-90 (HSP90) remains an important cancer target because of its involvement in multiple oncogenic protein pathways and biologic processes. Although many HSP90 inhibitors have been tested in the treatment of KRAS-mutant non–small cell lung cancer (NSCLC), most, including AUY9...
Autores principales: | Yoon, Shinkyo, Yang, Hannah, Ryu, Hyun-Min, Lee, Eunjin, Jo, Yujin, Seo, Seyoung, Kim, Deokhoon, Lee, Chang Hoon, Kim, Wanlim, Jung, Kyung Hae, Park, Sook Ryun, Choi, Eun Kyung, Kim, Sang-We, Park, Kang-Seo, Lee, Dae Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Cancer Association
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296920/ https://www.ncbi.nlm.nih.gov/pubmed/34607394 http://dx.doi.org/10.4143/crt.2021.651 |
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