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Hypo-trimethylation of Histone H3 Lysine 4 and Hyper-tri/dimethylation of Histone H3 Lysine 27 as Epigenetic Markers of Poor Prognosis in Patients with Primary Central Nervous System Lymphoma

PURPOSE: This study aimed to investigate the methylation status of major histone modification sites in primary central nervous system lymphoma (PCNSL) samples and examine their prognostic roles in patients with PCNSL. MATERIALS AND METHODS: Between 2007 and 2020, 87 patients were histopathologically...

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Detalles Bibliográficos
Autores principales: Kim, Hoon Gi, Kim, Minseok S., Lee, Young Sam, Lee, Eun Hee, Kim, Dae Cheol, Lee, Sung-Hun, Kim, Young Zoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296929/
https://www.ncbi.nlm.nih.gov/pubmed/34793663
http://dx.doi.org/10.4143/crt.2021.1121