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Splenic clearance of rigid erythrocytes as an inherited mechanism for splenomegaly and natural resistance to malaria
BACKGROUND: In malaria-endemic areas, subjects from specific groups like Fulani have a peculiar protection against malaria, with high levels of IgM but also frequent anaemia and splenomegaly. The mechanisms underlying this phenotype remain elusive. METHODS: In a cohort study set up in Benin, West Af...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297103/ https://www.ncbi.nlm.nih.gov/pubmed/35843175 http://dx.doi.org/10.1016/j.ebiom.2022.104167 |