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Splenic clearance of rigid erythrocytes as an inherited mechanism for splenomegaly and natural resistance to malaria

BACKGROUND: In malaria-endemic areas, subjects from specific groups like Fulani have a peculiar protection against malaria, with high levels of IgM but also frequent anaemia and splenomegaly. The mechanisms underlying this phenotype remain elusive. METHODS: In a cohort study set up in Benin, West Af...

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Detalles Bibliográficos
Autores principales: Henry, Benoît, Volle, Geoffroy, Akpovi, Hilaire, Gineau, Laure, Roussel, Camille, Ndour, Papa Alioune, Tossou, Félicien, Suarez, Felipe, Palstra, Friso, Fricot, Aurélie, Chambrion, Charlotte, Solinc, Julien, Nguyen, Julie, Garé, Mathilde, Aussenac, Florentin, Cottart, Charles-Henry, Keyser, Christine, Adamou, Rafiou, Tichit, Magali, Hardy, David, Fievet, Nadine, Clain, Jérôme, Garcia, André, Courtin, David, Hermine, Olivier, Sabbagh, Audrey, Buffet, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297103/
https://www.ncbi.nlm.nih.gov/pubmed/35843175
http://dx.doi.org/10.1016/j.ebiom.2022.104167