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A controversial issue: Can mitochondria modulate cytosolic calcium and contraction of skeletal muscle fibers?

Mitochondria are characterized by a high capacity to accumulate calcium thanks to the electrochemical gradient created by the extrusion of protons in the respiratory chain. Thereby calcium can enter crossing the inner mitochondrial membrane via MCU complex, a high-capacity, low-affinity transport me...

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Detalles Bibliográficos
Autores principales: Reggiani, Carlo, Marcucci, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297197/
https://www.ncbi.nlm.nih.gov/pubmed/35849108
http://dx.doi.org/10.1085/jgp.202213167